TABLE 1.

HAT inhibitor values^a

Inhibitor	Mean IC50 (μM) ± SD
	p300	PCAF	GCN5
Lys-CoA-Tat	0.25 ± 0.05	2.2 ± 0.4	2.3 ± 0.5
H3-CoA-20-Tat	12 ± 3	0.04 ± 0.01	N/D

^aAssays were performed as described in Materials and Methods. The IC₅₀ values are defined as the concentration of compound necessary to cause 50% inhibition of acetylation reaction. N/D, not done.