Table 2.
Demographic description of individuals with mosaicism for each cohort.
| ABC-DSa (N = 26) | Legacya (N = 45) | p-value | |
|---|---|---|---|
| Age (baseline) | |||
| Mean (SD) | 50.5 (8.9) | 55.64 (8.4) | 0.021 |
| Range | 33–65 | 43.01–78.08 | |
| Sex assigned at birth (% Female) | 38.5% | 57.7% | 0.12 |
| Intellectual impairment (% Mild or higher) | 53.8% | 36.4% | 0.15 |
| Race (% White) | 100% | 91.1% | 0.29 |
| APOE | |||
| APOE2 allele frequency | 14% | 11.1% | 0.71 |
| APOE4 allele frequency | 16% | 10% | 0.71 |
| AD Status | |||
| AD at baseline (%) | 19.2% | 8.88% | 0.27 |
| Converted to AD dementia in follow-up (%) | 14.3% | 21% | 0.74 |
a
Values are either means with standard variations and range for continuous variables, or percentages for categorical variables.