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. 2024 Oct 17;4(4):100412. doi: 10.1016/j.xagr.2024.100412

Table 2.

Preindex Clinical Characteristics by Racial Groups

Characteristic Optum Commercial
IBM Medicaid
White (n=46,139) Black (n=17,297) P-Valuea White (n=7353) Black (n=16,776) P-Valuea
CCI score, n (%) <.0001 <.0001
0 35,518 (77.0) 12,968 (75.0) 4026 (54.8) 9810 (58.5)
1 6999 (15.2) 2845 (16.4) 1962 (26.7) 4052 (24.2)
2 2274 (4.9) 759 (4.4) 691 (9.4) 1279 (7.6)
3+ 1348 (2.9) 725 (4.2) 674 (9.2) 1635 (9.7)
CCI score, mean (SD) 0.4 (0.9) 0.4 (1.1) <.0001 0.8 (1.4) 0.8 (1.5) NS
Most common individual CCI comorbidities, n (%)
Chronic pulmonary disease 4700 (10.2) 1783 (10.3) NS 2006 (27.3) 3697 (22.0) <.0001
Diabetes without chronic complication 2596 (5.6) 1589 (9.2) <.0001 1107 (15.1) 2736 (16.3) .0143
Any malignancy, including lymphoma and leukemia, except malignant neoplasm of skin 1594 (3.5) 354 (2.0) <.0001 232 (3.2) 386 (2.3) .0001
Comorbidities related to women's health, n (%)
Infertility 1097 (2.4) 451 (2.6) NS 35 (0.5) 135 (0.8) .0050
Pregnancy 1948 (4.2) 927 (5.4) <.0001 528 (7.2) 1385 (8.3) .0044
Uterine rupture 1 (0.0) 0 (0.0) NS 0 (0.0) 0 (0.0) NS
Endometriosis 2486 (5.4) 707 (4.1) <.0001 318 (4.3) 322 (1.9) <.0001
Uterine polyps 2123 (4.6) 500 (2.9) <.0001 242 (3.3) 310 (1.8) <.0001
Adenomyosis 501 (1.1) 164 (0.9) NS 137 (1.9) 153 (0.9) <.0001
Bulk symptoms, n (%)
Bulk symptoms 22,983 (49.8) 8586 (49.6) NS 5665 (77.0) 11,477 (68.4) <.0001
Abdominal distention 1171 (2.5) 328 (1.9) <.0001 222 (3.0) 336 (2.0) <.0001
Backache 8262 (17.9) 2886 (16.7) .0003 2894 (39.4) 4816 (28.7) <.0001
Constipation 1829 (4.0) 894 (5.2) <.0001 730 (9.9) 1644 (9.8) NS
Increased abdominal girth 1826 (4.0) 653 (3.8) NS 339 (4.6) 665 (4.0) .0207
Leg pain 4537 (9.8) 1813 (10.5) .0154 1624 (22.1) 3129 (18.7) <.0001
Pelvic pressure/pain 12,418 (26.9) 4871 (28.2) .0017 3990 (54.3) 7916 (47.2) <.0001
Urinary frequency/incontinence 4647 (10.1) 1591 (9.2) .0010 1427 (19.4) 2416 (14.4) <.0001
Mental health disorder, n (%)
Anxiety 6920 (15.0) 1588 (9.2) <.0001 2993 (40.7) 2976 (17.7) <.0001
Depression 5795 (12.6) 1415 (8.2) <.0001 2802 (38.1) 3898 (23.2) <.0001
Gastrointestinal conditions, n (%)
Diarrhea 2013 (4.4) 629 (3.6) <.0001 795 (10.8) 1019 (6.1) <.0001
Nausea/vomiting 3350 (7.3) 1451 (8.4) <.0001 1785 (24.3) 3057 (18.2) <.0001
Other conditions, n (%)
Hypertension 8824 (19.1) 5309 (30.7) <.0001 2398 (32.6) 7389 (44.0) <.0001
Hyperlipidemia 8496 (18.4) 3098 (17.9) NS 1794 (24.4) 3196 (19.1) <.0001
Urinary tract infection 5912 (12.8) 2384 (13.8) .0013 1840 (25.0) 3717 (22.2) <.0001
Fatigue 8664 (18.8) 2774 (16.0) <.0001 1748 (23.8) 2844 (17.0) <.0001
Anemia 1648 (3.6) 1028 (5.9) <.0001 331 (4.5) 1180 (7.0) <.0001
Obesity 5538 (12.0) 3101 (17.9) <.0001 1886 (25.6) 4841 (28.9) <.0001

CCI, Charlson Comorbidity Index; NS, not significant; SD, standard deviation.

a

Comparisons are White vs Black women.

Agarwal. Uterine fibroids with heavy menstrual bleeding stratified by race in a commercial and Medicaid database. Am J Obstet Gynecol MFM 2024.