Table 3.
The average lifetime of R9 aggregates (in ps) of different sizes (dimer–heptamer and higher aggregates) at the POPC bilayer for low and high peptide concentrations in systems with different salt compositions and concentrations. The error bar is the standard deviation of the mean value when multiple aggregation events occur. The range of aggregate lifetimes is presented for larger aggregates (> heptamer).
| system | dimer | trimer | tetramer | pentamer | hexamer | heptamer | > heptamer |
|---|---|---|---|---|---|---|---|
| Water |
a 297 ± 38 b 799 ± 50 |
– 335 ± 20 |
– 270 ± 32 |
– 207 ± 43 |
– 150 ± 29 |
– – |
– – |
| 0.133 m NaCl | 492 ± 88 857 ± 60 |
– 360 ± 22 |
– 287 ± 25 |
– 218 ± 23 |
– 140 ± 21 |
– 220 ± 58 |
– – |
| 1.065 m NaCl | 928 ± 103 638 ± 26 |
652 ± 141 425 ± 18 |
380 ± 77 352 ± 18 |
c∼300 241 ± 17 |
– 258 ± 21 |
– 159 ± 13 |
– 150 – 200 |
| 0.133 m CaCl2 | 760 ± 119 561 ± 31 |
231 ± 55 337 ± 19 |
c∼100 254 ± 20 |
– 159 ± 71 |
– 129 ± 14 |
– 217 ± 48 |
– c∼100 |
| 1.065 m CaCl2 | 1030 ± 144 659 ± 48 |
493 ± 53 443 ± 31 |
366 ± 65 321 ± 23 |
138 ± 18 273 ± 20 |
– 237 ± 20 |
– 244 ± 19 |
– 150 – 250 |
The upper row shows data for low peptide concentration.
The lower row shows data for high peptide concentration.
A single continuous aggregation event.