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. 2024 Oct 23;4:103920. doi: 10.1016/j.bas.2024.103920

Table 1.

Overview of the clinical and demographic characteristics of the present case as well as of the only eigth cases of liposarcoma already documented in the literature, and comparison of treatments applied in each case and their results.

Study Sarcoma subtype Age (years) Sex Localization Clinical Data Initial Treatment Result Follow-up
presentcase DDLPD 36 f thoracic(T5/T6) Paresisofbothlegs.Paresthesiaofbothlegs,ascendingintosupraum-bilicalregion.2-dayterm LaminectomyofT6andinternalstabilizationT5toT7.Chemotherapy(doxorubicin+ifosfamide,3courses).ResectionofT6withdorsalinstrumentationfromT5toT7andventralre-constructionplusresectionofcostae5to7.60,4Gy radiationtherapy. Neurologicalrecovery.Stiffnessinthethoracicregionofthespine.Deafnessalongintercostalnerves. 53 months.Nolocalrecurrenceormetastasis.
Turanli et al. (2000) MLPS 65 f lumbar Low back pain. Weakening of left ante-rior tibial muscle (Grade 4/5). Hyperactivity in left L4 dermatoma. Positive Lasègue test at 60° on left side. 6-week term. Hemilaminectomy of L3. Marginal resection of the tumor. Posterior pedicle screws from L2 to L4. No problems in performing daily activities. 13 months. No local recurrence or metastasis.
Kaneuchi et al. (2016) MLPS 22 f thoracic Back pain. Hypalgesia and hypesthesia below level of the xiphoid cartilage. Numbness of the lower extremities. Laminectomy of T4 – T6. Intralesional resection. Chemotherapy (doxorubicin + ifosfamide, 3 courses). Rapid recovery of paralysis without any disturbance. 18 months. No local recurrence or metastasis.
Rovlias et al. (2017) MLPS 79 m thoracic Aggravating weakness of lower limbs. Posterior pain. Spastic paraparesis with a fifth thoracic sensory level. 2-month term. Laminectomy of T4 and T5. Piece-meal subtotal excision of tumor. T3 to T7 posterior ins-trumentation. 45Gy palliative radiotherapy. No functional neurological improvement. Significant dorsal pain relief. 7 months. Gradual physical deterioration. Death.
Zhao et al., (2016) (3 cases) MLPS

44

m

sacral

Low back pain. Radicular pain, numbness and weakness of the left leg. Weight decrease.

Piece-meal resection. Lumbar-iliac fusion.

No details given.

18 months. Local recurrence and metastasis. Death.

MLPS 37 m lumbar (L4-ilium) Low back pain. Radicular pain, numbness and weakness of the lower extremities. Piece-meal resection. Lumbar-iliac fusion. No details given. 20 months. No evidence of disease.
MLPS 32 m cervical (C1-4) Neck pain and limitation of neck motion. Palpable mass. Piece-meal resection. Occipital fusion. No details given. 20 months. Local recurrence and metastasis. Alive.
Hamlat et al. (2005) PLPS 45 f thoracic (T7/T8) Backache. Paraplegia. Sensory level at T4. Clonus and bilateral extensor plantar reflex. Laminectomy + instrumentation +45 Gy radiation therapy. No neurological improvement (paraplegia). Lung and costal area were irradiated. 13 months. Physical deterioration. Alive.
Lmejjati et al. (2008) PLPS 35 m lumbar (L4/L5) Bilateral lumbosciatica. Gait abnormality. Cauda equina syndrome. No alteration in the sphincters. 2-month term. Surgical decompression + 45Gy radiation therapy. Neurological recovery. Death at 3 months. 3 months. Death.
de Moraes et al. (2012) PLPS 60 f lumbar (L4) Lumbosciatica on the left side. No motor or sensory deficit. 6-month term. Resection of L4, L3 to L5 arthrodesis. Radiation therapy, chemotherapy. At 18 months, neither pain, nor neurologic deficit, recurrence, or metastasis. 36 months. Lung metastasis.
Halevi et al. (2015) PLPS 70 m thoracic (T5) Sudden onset lower extremity weakness. Constipation. Back pain. Emergency decompressive laminectomy of T5 and T6. Radiation therapy. Tumor recurrence after 3 months with repeat surgery, radiation and chemotherapy. 12 months. Widespread metastasis. Death.
Morales-Codina et al. (2016) PLPS 61 m lumbar (L1-L3) Bilateral lumbosciatica. Motor deficit in the lower limbs. Hypoesthesia in L1, L2, and L3. No alteration in the sphincters. Change in gait. 4-month term. En-bloc resection in L1, L2 and L3 + instrumentation. Dehiscence and a deep wound infection. Inflamma-tory polymyopathy. 2 months. Local recurrence. Hepatic metastasis. Extensive thrombosis. Type I hepato-renal syndrome. Death.