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. 2024 Nov 1;13:101780. doi: 10.1016/j.toxrep.2024.101780

Table 1.

Brief history of pesticide use (Source: PubChem.com).

Time period Type of pesticide use
Ancient time Ashes, blisters, and common salts
1st century to 15th century Arsenic, a suggestion of soda and olive oil for the treatment of legumes (Pliny the Elder, a Roman naturalist-Historia Naturalis)
16th century to the of the 18th century Arsenicals and nicotine in the form of tobacco extracts (Chinese farmers)
1850–1866 Pyrethrum, soap, and a wash of tobacco, sulfur, and lime are also used
1867–1895 The pigment Paris green (an impure form of copper arsenite), Paris green, and kerosene oil emulsion
1896–1899 Bordeaux mixture (CuSO4 and Ca (OH)2) and selective chemical herbicides
1900–1960 Dilute sulfuric acid, copper nitrates, and potassium salts
Sodium arsenite solutions become the standard herbicides and are used in large quantities. Organomercury seed dressing. Dithiocarbamates fungicides used in the US.
1961 DDT is registered for use on 34 different crops as pesticide usage dramatically increases
1962–1971 Stoppage of DDT usage and other chlorinated compounds by farmers. Favor of the use of Organophosphates and Carbamates
1972 Environmental Protection Agency revoked the use of DDT on all food sources in the United States. The World Health Organization, however, still reserves the right to use DDT on particularly virulent outbreaks of malaria.
1973–1989 Herbicidal sulfonylureas, neonicotinoids, glyphosate, synthetic fungicides such as metaxyl and triadimefron, and light-stable pyrethroid pesticides are introduced
1990–1999 Integrated pest management, intensified research on biological pest control methods and other alternatives to pesticides
2000–2009 Widespread usage of IPM techniques in organic farming excluding the usage of synthetic pesticides.
2010–2015 Involvement of genetic engineering and biotechnological methods to control the usage of pesticides eg. Baculoviruses
2016–2022 Acetamiprid, Allethrin, Bendiocarb, Bifenthrin, Carbaryl, Cyphenothrin, Difenconazole, D-trans Allethrin, Fipronil, Imidachloprid, Limda-cyahalothrin, Profenofos, Thiamethoxam, Dodine, Hexaconazole, Propineb, Thiophanate-Methyle, Tricyclazole, Metribuzin, Oxyfluorfen, Bromadiolone, etc.