Fig. 1. Depiction of galectin-1 (Gal-1) PDB ID: 4Y24 (green) bound to the co-crystal TD-139 (cyan). The structure represents a single chain of the Gal-1 dimer, with strands S1–S6 labelled. The carbohydrate-binding site (CBS) is circled with a red dotted line, located among strands S4–S6. The carbohydrate recognition domain (CRD) is highlighted by a black bracket. Key residues responsible for sugar recognition, His52 and Trp68, are shown in magenta. The loops have been smoothened for representational purposes.