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CD spectra of free calf thymus DNA (230 μM base pair) before and after its incubation with both complex photoisomers (2 h of incubation) and with cisplatin (20 h of incubation) as a positive reference. The concentration of all platinum compounds was 250 μM. Inset: the interaction kinetics tracked at 275 nm. All measurements were performed in 10 mM sodium phosphate buffer pH 7.4 at 25 °C.
