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. 2024 Oct 24;67(21):19103–19120. doi: 10.1021/acs.jmedchem.4c01575

Figure 8.

Figure 8

Cytotoxicity of trans-2, cis-2, and cisplatin in the 4T1 murine mammary cancer (A,B) and normal NMuMG (C,D) cell line after 24 (A,C) and 48 h (B,D) of cell culture determined with the MTT test. The culture medium (DMEM—high glucose) was supplemented with 10% FBS. The numbers denote the cis/trans, cisplatin/cis, and cisplatin/trans viability ratios at respective concentrations. Statistically significant differences are indicated with asterisks above the bars (difference from the control) and above the brackets (difference between the photoisomers and between cisplatin and either of the photoisomers), *p < 0.05.