Table 3.
Comparison of the general conditions and ccf-mtDNA content among patients with different K-L grades of KOA
| K-L n | I 9 | II 22 | III 18 | IV 11 | P value |
|---|---|---|---|---|---|
| Age (mean ± SD) | 54.44 (9.52) | 60.59 (11.00) | 61.56 (9.65) | 64.82 (7.14) | 0.136 |
| Female (%) | 66.67 | 86.36 | 72.22 | 90.91 | 0.409 |
| Height (mean ± SD) | 1.62 (0.06) | 1.58 (0.05) | 1.59 (0.07) | 1.57 (0.04) | 0.261 |
| Weight (mean ± SD) | 64.44 (13.58) | 59.77 (13.58) | 59.67 (5.54) | 59.00 (7.73) | 0.563 |
| BMI (mean ± SD) | 24.39 (4.01) | 23.95 (2.34) | 23.81 (3.27) | 23.94 (3.37) | 0.975 |
| WOMAC (mean ± SD) | |||||
| Total score | 18.89 (3.72) | 34.18 (9.06) | 56.72 (12.18) | 90.18 (12.80) | < 0.0001 |
| Pain score | 7.89 (2.15) | 10.14 (2.66) | 15.28 (3.21) | 23.45 (4.13) | < 0.0001 |
| Stiffness score | 3.56 (1.59) | 4.91 (1.66) | 7.28 (1.74) | 10.45 (1.64) | < 0.0001 |
| Physical function score | 7.44 (1.94) | 19.14 (6.66) | 33.61 (7.46) | 56.18 (8.60) | < 0.0001 |
| ccf-mtDNA content (median, quartile range) | 1.22 (0.84–2.65) | 2.26 (0.98–3.12) | 3.45 (1.50–4.66) | 4.52 (1.09–5.84) | 0.040 |