Table 6.
Association of plasma ccf-mtDNA content with KOA risk stratified by host characteristics
| Variables | ccf-mtDNA | KOA | HC | OR (95% CI) | P value |
|---|---|---|---|---|---|
| Age | |||||
| ≤ 60.1 | Lower | 5 | 15 | 1 | 0.005 |
| Higher | 29 | 21 | 7.49 (1.83–30.70) | ||
| > 60.1 | Lower | 9 | 15 | 1 | 0.203 |
| Higher | 17 | 9 | 2.31 (0.64–8.42) | ||
| Gender | |||||
| Female | Lower | 12 | 22 | 1 | 0.012 |
| Higher | 36 | 26 | 3.63 (1.33–9.92) | ||
| Male | Lower | 2 | 8 | 1 | 0.030 |
| Higher | 10 | 4 | 9.76 (1.25–76.10) | ||
| Height | |||||
| ≤ 1.59 | Lower | 9 | 14 | 1 | 0.035 |
| Higher | 29 | 24 | 3.94 (1.10–14.10) | ||
| > 1.59 | Lower | 5 | 16 | 1 | 0.004 |
| Higher | 17 | 6 | 8.84 (2.04–38.36) | ||
| Weight | |||||
| ≤ 60 | Lower | 7 | 15 | 1 | 0.008 |
| Higher | 30 | 21 | 6.29 (1.62–24.47) | ||
| > 60 | Lower | 7 | 15 | 1 | 0.211 |
| Higher | 16 | 9 | 2.39 (0.61–9.31) | ||
| BMI | |||||
| ≤ 23.69 | Lower | 6 | 20 | 1 | 0.001 |
| Higher | 26 | 15 | 8.34 (2.27–30.70) | ||
| > 23.69 | Lower | 8 | 10 | 1 | 0.355 |
| Higher | 20 | 15 | 1.88 (0.49–7.18) | ||
Adjusted for age, gender, height, weight, and BMI where appropriate