Table 3.
One-Way Sensitivity Analysis Scenario Results.
| (U.K. Case) | Average Cost (GBP) | Average QALYs | QALY Difference | Cost Difference (GBP) | ICER (GBP/QALY) |
|---|---|---|---|---|---|
| Base case—control | 216 980 | 19.30 | 1.14789 | 22,181 | 19 323 |
| Base case—treatment (CL) | 239 161 | 20.44 | |||
| Algorithm cost only—control | 216 980 | 19.30 | 1.15302 | 11,641 | 10 096 |
| Algorithm cost only—treatment (CL) | 228 621 | 20.45 | |||
| 60% Effectiveness—control | 216 980 | 19.30 | 0.74302 | 24,443 | 32 897 |
| 60% Effectiveness—treatment (CL) | 241 423 | 20.04 | |||
| Algorithm cost only and 60% effectiveness—control | 216 980 | 19.30 | 0.74302 | 13,875 | 18 674 |
| Algorithm cost only and 60% effectiveness—treatment (CL) | 230 855 | 20.04 | |||
| U.S. Case | Average Cost (USD) | Average QALYs | QALY Difference | Cost Difference (USD) | ICER (USD/QALY) |
| Base case—control | 757 670 | 18.44 | 1.51865 | −5949 | −3917 |
| Base case—treatment (CL) | 751 721 | 19.96 | |||
| Algorithm cost only—control | 757 670 | 18.44 | 1.51865 | −54,312 | −35 763 |
| Algorithm cost only—treatment (CL) | 703 358 | 19.96 | |||
| 60% Effectiveness—control | 757 670 | 18.44 | 1.04883 | 21,859 | 20 841 |
| 60% Effectiveness—treatment (CL) | 779 529 | 19.49 | |||
| Algorithm cost only and 60% effectiveness—control | 757 670 | 18.44 | 1.04883 | −31,514 | −30 047 |
| Algorithm cost only and 60% effectiveness—treatment (CL) | 726 156 | 19.49 |