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. Author manuscript; available in PMC: 2024 Nov 18.
Published in final edited form as: Am J Kidney Dis. 2023 May 13;82(4):464–480. doi: 10.1053/j.ajkd.2023.02.008

Table 1.

Measures of PDF

References Measure Benefits Limitations
Lindsay, et al. 200625
Awuah, et al. 201328
Bossola, et al. 201327
Rayner, et al. 201429
Hussein, et al. 201731
Davenport, et al. 201830
Alvarez, et al. 20208
Brys, et al. 202026
Guerraoui, et al. 202120
  • Time to recovery from dialysis (TIRD)

  • Patients were asked “how long does it take you to recover from a dialysis session?”

  • No consensus between studies of how to report this, either as a continuous or a categorical measure

  • Easily interpreted, elicits a clear response, and stable on test-retest25

  • Has been used across several studies

  • Does not incorporate multiple dimensions of fatigue such as severity or frequency

  • No consensus on how to report values

  • Moderately associated with fatigue severity, quality of life, other dialysis-associated symptoms, psychosocial stressors, and ability to engage in social-leisure activity.25

Sklar, et al. 199617
Sklar, et al. 199816
Sklar, et al. 199915
Gordon, et al. 201118
Bossola, et al. 201823
Bossola, et al. 202024
Bossola, et al. 202322
  • Quantify duration, frequency, and intensity of fatigue on 5-point Likert scales

  • If the average of these was ≥4 the patient was considered to have post-dialysis fatigue

  • Incorporates multiple dimensions of PDF

  • Has been used across several studies

  • Variability between patients in interpreting Likert scales

Dubin, et al. 201319
  • Patients answering yes to “after most dialysis sessions, do you have fatigue for 2 hours or less?” were defined as having mild post-dialysis fatigue.

  • Patients answering yes to “after most dialysis sessions, do you have fatigue for more than 2 hours?” were defined as having severe post-dialysis fatigue.

  • Simple and straightforward

  • Does not incorporate multiple dimensions of fatigue such as severity or frequency

  • Does not capture total PDF duration

Guerraoui, et al. 202120
  • Assessed prevalence with a binary question

  • Assessed intensity on a visual analog scale

  • Assessed recovery time on a Likert scale

  • Assesses multiple dimensions of fatigue

  • Variability between patients in interpreting Likert scales and visual analog scales

Brys, et al. 202032
  • Used an experience sampling method to assess fatigue in real time via a smart phone app

  • Gathers data prospectively so is less limited by recall bias than other methods

  • Patients reporting fatigue were separately asked about their degree of mental and physical fatigue

  • Captures changes in a person’s level of fatigue over the course of a day

  • May not be accessible to all

  • More time consuming than other methods

Abbreviations: PDF, post-dialysis fatigue; TIRD, time to recovery from dialysis