Table 1.
Comparison of CGM-Derived Measures of Glycemic Variability for Participants Across 24 hours, Daytime (06:00-22:00 h) and Overnight (22:00-06:00 h). Where Appropriate, Data Are Presented as Mean ± SD (n = 12).
| 24 h | Daytime (06:00-22:00 h) | Overnight (22:00-06:00 h) | ||
|---|---|---|---|---|
| MG | mg dL−1 (mmol L−1) | 102.6 ± 5.4 (5.7 ± 0.3) | 108 ± 3.6 (6.0 ± 0.2)* # | 91.8 ± 5.4 (5.1 ± 0.3)* |
| MODD | mg dL−1 (mmol L−1) | 12.6 ± 1.8 (0.7 ± 0.1) | 16.2 ± 1.8 (0.9 ± 0.1)*# | 9.0 ± 1.8 (0.5 ± 0.1)* |
| MAGE | mg dL−1 (mmol L−1) | 36.0 ± 5.4 (2.0 ± 0.3) | 39.6 ± 5.4 (2.2 ± 0.3) # | 25.2 ± 7.2 (1.4 ± 0.4)* |
| SD | mg dL−1 (mmol L−1) | 16.2 ± 1.8 (0.9 ± 0.1) | 18.0 ± 1.8 (1.0 ± 0.1) # | 10.8 ± 3.6 (0.6 ± 0.2)* |
| AUC | mg dL−1 (mmol L−1 h−1) | 6093 ± 280.8 (338.5 ± 15.6) | 6396.2 ± 270.0 (355.4 ± 15.0)* # | 5581.8 ± 268.2 (310.1 ± 14.9)* |
| % CV | 0.2 ± 0.0 | 0.2 ± 0.0 | 0.1 ± 0.0 | |
| Hypoglycemia >72.0 mg/dL | % | 0.5 (7.3) | 0.0 (3.0) | 0.8 (22.5) |
| Euglycemia 72.0-144.0 mg/dL | % | 96.3 ± 2.4 | 96.0 ± 2.4 | 99.3 (22.5) |
| Hyperglycemia >144.0 mg/dL | % | 2.4 ± 1.6 | 3.5 ± 2.4 # | 0.0* |
CGM: continuous glucose monitor; MG: mean glucose; MODD: mean of daily differences; MAGE: mean amplitude of glycemic excursion; SD: standard deviation; %CV: percentage coefficient of variation for glucose.
*
Denotes significant difference from 24 hours (P < .02).
#
Denotes significant difference from overnight (P < .0001).