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. 2024 Jun 17:0271678X241262127. Online ahead of print. doi: 10.1177/0271678X241262127

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© The Author(s) 2024

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Figure 5. — Transcriptomic analysis of hypertensive and stroke brains within the prefrontal cortex. Volcano plots of the log₁₀ adjusted p-value vs log₂ fold change of differentially expressed genes in the (a) hypertensive (HT) + Sham vs normotensive (NT) + Sham, (c) NT + Stroke vs NT + Sham, and (e) HT + Stroke vs normotensive stroke NT + Stroke comparison. Heat map analysis of the top 10 up- and downregulated neuroinflammatory genes in the (b) HT + Sham vs NT + Sham, (d) NT + Stroke vs NT + Sham, and (f) HT + Stroke vs NT + Stroke comparison. Gene expression is shown as log₁₀(FPKM +1) with a p-value threshold of <0.05.