Table 1. Characteristics of the included studies about country, type of disease, form of supplement, age, and duration consumption probiotic.

No	Author (Reference)	Country	Type of disease	Form of supplement	Age (y)	Duration (weeks)
1	Han et al.11, 2012	Korea	Atopic dermatitis	Yogurts	1-13	12
2	Harima-Mizusawa et al.14, 2016	Japan	Allergic rhinitis	Juice	16-65	8
3	Ishida et al.15, 2005	Japan	Allergic rhinitis	Milk	34-36	8
4	Kawase et al.17, 2009	Japan	Japanese cedar pollinosis	Milk	20-57	10
5	Hummelen et al.19, 2011	Canada	HIV	Yogurts	>18	4
6	Parra et al.20, 2004	Spain	Healthy person	Yoghurt	51-58	8
7	Bunout et al.21, 2004	Switzerland	Healthy eldery	Powder	>70	16
8	Miyazawa et al.22, 2015	Japan	Healthy eldery	Tablet	50-70	4
9	Mangalat et al.23, 2012	America	Healthy adults	Tablet	19-60	8
10	Drago et al.13, 2011	Italy	Atopic dermatitis	Powder	10-46	16
11	Tamura et al.27, 2007	Japan	Allergic rhinitis	Milk	x=39	8
12	Hasegawa et al.18, 2009	Japan	Japanese cedar polinosis	Milk	x=35	8
13	Ivory et al.16, 2008	UK	Allergic rhinitis	Yogurt	18-45	2
14	Hirose et al.24, 2006	Japan	Healthy subjects	Capsule	40-64	12
15	Seifert et al.25 2011	Germany	Healthy individuals	Milk	18-60	4
16	Meyer et al.28 2007	Austria	Healthy young women	Yogurt	22-29	2
17	Costabile et al.29, 2017	UK	Hypercholesterolaemic	Capsular	30-65	12
18	Ahn et al.12, 2020	Korea	Atopic Dermatitis	Tablet	2-13	12
19	Baroja et al.<sub>26</sub>, 2007	Canada	Inflammatory bowel disease	Yogurt	26-63	4
20	Ouwehand et al.30, 2008	Finland	Healthy elderly	Powder	>65	2

x= mean of age. HIV: Human immunodeficiency virus