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. 2024 Oct 3;20(37):2971–2982. doi: 10.1080/14796694.2024.2404762

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© 2024 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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graphic file with name IFON_A_2404762_F0002A_C.jpg — Landmark analysis of PFS (BIRC review) and OS in patients treated with dacomitinib according to whether they experienced a grade ≥2 skin-related AE at landmark time points.^a (A) PFS at 3 months, (B) PFS at 6 months, (C) OS at 3 months. and (D) OS at 6 months

AE: Adverse event; BIRC: Blinded independent radiological central; CI: Confidence interval; HR: Hazard ratio; NR: Not reached; PFS: Progression-free survival.

^aPatients with a PFS time less than or equal to the landmark time were excluded from the corresponding analysis.

graphic file with name IFON_A_2404762_F0002B_C.jpg — Landmark analysis of PFS (BIRC review) and OS in patients treated with dacomitinib according to whether they experienced a grade ≥2 skin-related AE at landmark time points.^a (A) PFS at 3 months, (B) PFS at 6 months, (C) OS at 3 months. and (D) OS at 6 months

AE: Adverse event; BIRC: Blinded independent radiological central; CI: Confidence interval; HR: Hazard ratio; NR: Not reached; PFS: Progression-free survival.

^aPatients with a PFS time less than or equal to the landmark time were excluded from the corresponding analysis.