Table 4.
Heart Rate Variability (HRV) Parameters Before and After Administration of Medication.
| Variable | Group 1 (Detoxification) (n = 39) |
Group 2 (OST) (n = 40) |
||
| Pre | Post | Pre | Post | |
| Heart rate | 82.351 (16.326) |
85.501 (14.944) |
92.374 (18.631) |
90.329 (16.151) |
| SDNN | 136.983 (240.988) |
110.92 (215.122) |
47.67 (62.029) |
50.827 (55.234) |
| RMSSD | 185.172 (375.04) |
148.755 (319.367) |
52.522 (89.19) |
54.665 (74.42) |
| RR tri-index | 8.992 (5.346) |
8.645 (5.405) |
5.025 (2.788) |
5.799 (2.546) |
| VLF | 0.034 (0.009) |
0.035 (0.011) |
0.033 (0.013) |
0.034 (0.012) |
| LF | 0.086 (0.033) |
0.097 (0.033) |
0.092 (0.04) |
0.084 (0.035) |
| HF | 0.225 (0.071) |
0.202 (0.055) |
0.208 (0.069) |
0.203 (0.073) |
| VLF percentage | 12.013 (17.815) |
7.196 (8.56)* |
13.532 (14.512) |
13.672 (14.492) |
| LF percentage | 49.456 (23.866) |
54.827 (21.745) |
42.305 (22.779) |
48.258 (20.911) |
| HF percentage | 38.441 (25.081) |
37.92 (23.825) |
44.024 (30.794) |
37.969 (25.266) |
| LF/HF ratio | 3.593 (7.67) |
2.957 (3.295) |
3.624 (5.728) |
3.529 (4.513) |
| Total power ms2 | 100772.159 (425559.25) |
76528.363 (202185.322) |
2796.056 (6912.399) |
5317.385 (12799.504) |
The table presents the HRV parameters before and after buprenorphine administration in the detoxification and opioid substitution treatment groups.
HF, high frequency; HRV, heart rate variability; LF, low frequency; OST, opioid substitution treatment; RMSSD, root mean square of successive differences between normal heartbeats; SDNN, standard deviation of all normal RR (NN) intervals; VLF, very low frequency,
*Difference between pre- and post-significant at P value <.05