Figure 1.

White matter lesions with central vein sign and paramagnetic rim in patients with pediatric multiple sclerosis. Axial fluid‐attenuated inversion recovery (FLAIR) sequence showing a confluent lesion (A) with multiple veins within its context on FLAIR* (B). Axial (C,E) FLAIR sequences showing brain T2‐hyperitense white matter lesions that, on FLAIR* (D,F) demonstrate a central vein sign (red triangles). In (F) the central vein sign is visible in the three plains (axial, sagittal, and coronal). Axial FLAIR sequence (G) showing a brain T2‐hyperitense white matter lesion that, on phase image (H), demonstrates a paramagnetic rim (blue triangle). See text for further details.