Table 1.
Total (n=3407) | High-income countries (n=2296) | Upper-middle income countries (n=677) | Lower-middle income countries (n=377) | Low-income countries (n=57) | P | |
---|---|---|---|---|---|---|
Sex | ||||||
Male | 844 (24.8%) | 571 (24.9%) | 161 (23.8%) | 103 (27.3%) | 9 (15.8%) | 0.067 |
Female | 2500 (73.4%) | 1722 (75.0%) | 491 (72.5%) | 239 (63.4%) | 48 (84.2%) | |
Missing | 63 (1.8%) | 3 (0.1%) | 25 (3.7%) | 35 (9.3%) | ||
Median age at diagnosis, days | 0 (0–54) | 0 (0–17.5) | 1 (0–108.5) | 8 (0–150) | 30 (2.5–556.5) | <0.001 |
Altman classification | ||||||
I | 1036 (30.4%) | 669 (29.1%) | 227 (33.5%) | 125 (33.2%) | 15 (26.3%) | <0.001 |
II | 1118 (32.8%) | 753 (32.8%) | 201 (29.7%) | 137 (36.3%) | 27 (47.4%) | |
III | 609 (17.9%) | 407 (17.7%) | 130 (19.2%) | 63 (16.7%) | 9 (15.8%) | |
IV | 548 (16.1%) | 432 (18.8%) | 851 (12.6%) | 25 (6.6%) | 6 (10.5%) | |
Missing | 96 (2.8%) | 35 (1.5%) | 34 (5.0%) | 27 (7.2%) | – | |
Median age at resection, days | 13 (4–134.3) | 9 (3–99) | 17 (6–187.3) | 40 (14–271.5) | 52 (14.0–570) | <0.001 |
Pathology | ||||||
Mature | 2168 (63.7%) | 1504 (65.5%) | 442 (65.3%) | 184 (48.8%) | 38 (66.7%) | 0.004 |
Immature | 625 (18.3%) | 469 (20.4%) | 91 (13.4%) | 54 (14.3%) | 11 (19.3%) | |
Malignant | 366 (10.7%) | 245 (10.7%) | 91 (13.4%) | 27 (7.2%) | 3 (5.3%) | |
Missing | 248 (7.3%) | 78 (3.4%) | 53 (7.8%) | 112 (29.7%) | 5 (8.8%) | |
Recurrence | ||||||
Yes | 349 (10.2%) | 254 (11.1%) | 56 (8.3%) | 33 (8.8%) | 6 (12.3%) | 0.604 |
No | 2829 (83.0%) | 1967 (85.7%) | 536 (79.2%) | 276 (73.2%) | 50 (87.7%) | |
Missing | 229 (6.8%) | 75 (3.3%) | 85 (12.6%) | 68 (18.0%) | 1 (1.8%) | |
Median time between primary resection and recurrence, days | 348 (196–666) | 348 (200.5–679) | 358 (182.5–673.8) | 357 (195.5–668) | 311.5 (131.5–654.5) | 0.948 |
Recurrence pathology | ||||||
Mature | 117 (33.5%) | 96 (37.8%) | 14 (25.0%) | 7 (21.2%) | – | 0.001 |
Immature | 34 (9.7%) | 23 (9.1%) | 4 (7.1%) | 7 (21.2%) | – | |
Malignant | 126 (36.1%) | 91 (35.8%) | 22 (39.3%) | 7 (21.2%) | 6 (100%) | |
Missing | 72 (20.6%) | 44 (17.3%) | 16 (28.6%) | 12 (36.4%) | – | |
Outcome | ||||||
Alive | 2876 (84.4%) | 2073 (90.3%) | 534 (78.9%) | 219 (58.1%) | 50 (87.7%) | 0.059 |
Death | 140 (4.1%) | 93 (4.1%) | 25 (3.7%) | 20 (5.3%) | 2 (3.5%) | |
Missing | 391 (11.5%) | 130 (5.7%) | 118 (17.4%) | 138 (36.6%) | 5 (8.8%) |
Data are n (%) or median (IQR).
P values represent univariable testing between country income strata.