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. 2024 Sep 19;137(5):1434–1445. doi: 10.1152/japplphysiol.00463.2024

Table 4.

Linear regression results

(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
(10)
CR CR eGFR eGFR CK CK ALT ALT AST AST
Sex 0.37 (0.03)*** 0.31 (0.05)*** −3.86 (2.61) −2.35 (3.70) 2,741.10 (378.51)*** 707.19 (538.56) 93.85 (14.80)*** 81.41 (25.98)** 103.57 (15.45)*** 61.00 (21.08)**
Age −0.01 (0.00)** −0.17 (0.25) −289.34 (52.35)*** 1.02 (1.87) −2.92 (1.55)
Height, cm −0.14 (0.10) 0.82 (5.00) −3,373.10 (1,598.96)* −26.69 (37.66) −207.26 (56.11)***
Weight, kg −0.15 (0.08) 3.39 (3.86) −3,107.54 (1,286.43)* 21.69 (35.24) −148.27 (46.34)**
BSA 16.42 (10.28) −243.59 (500.69) 36,0944.69 (16,5840.60)* 1,097.07 (4,021.76) 20,800.80 (5,862.12)***
BSA:mass 148.62 (168.89) 1,242.08 (8,838.48) 2.18e+06 (2.61e+06) 181,493.78 (69,107.26)** 347,807.84 (92,011.34)***
Observations 462 462 454 454 442 442 452 452 452 452
R-squared 0.390 0.448 0.382 0.446 0.073 0.142 0.235 0.283 0.163 0.247

Robust standard errors in parentheses. All models include a time fixed effect. *P < 0.05, **P < 0.01, ***P < 0.001. ALT, alanine aminotransferase; AST, aspartate aminotransferase; BSA, body surface area; BSA:mass, body surface area to mass ratio; CK, creatine kinase; CR, creatinine, eGFR, estimated glomerular filtration rate.