Table A4.
Mixed-effects regression results to test mean difference for women
| (1) |
(2) |
(3) |
(4) |
|
|---|---|---|---|---|
| CK | AST | ALT | CR | |
| Time = 2 | −36.38 (226.57) | −1.70 (11.25) | −2.77 (7.07) | −0.45 (0.04)*** |
| Time = 3 | −83.28 (226.58) | 0.82 (11.25) | −0.85 (7.07) | −0.47 (0.04)*** |
| Time = 4 | −197.27 (236.69) | 2.59 (12.38) | 2.77 (7.79) | −0.53 (0.04)*** |
| Time = 5 | −436.41 (226.58) | 9.32 (11.25) | 10.40 (7.07) | −0.55 (0.04)*** |
| Time = 6 | −444.89 (236.41) | 44.30 (11.74)*** | 40.32 (7.38)*** | −0.55 (0.04)*** |
| Constant | 517.18 (291.84) | 0.45 (8.40) | −22.18 (5.83)*** | 0.31 (0.04)*** |
| Observations | 49 | 48 | 48 | 48 |
| AIC | 705 | 423 | 387 | −41 |
Mixed-effects models calculated using restricted maximum likelihood with the Kenward–Roger method. Standard errors in parentheses. AIC, Akaike information criterion; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CK, creatine kinase; CR, creatinine. *P < 0.05, **P < 0.01, ***P < 0.001.