FIGURE 6.

The CSP inhibited de novo lipogenesis and IR by regulating the LXRα/SREBP-1 signing pathway. (A, B) FFA and DAG content in hepatocytes. (C) Representative images of immunofluorescent staining of LXRα in hepatocytes (scale bar: 20 μm). (D, E) The protein expression levels of LXRα, SREBP-1, FASN, and ACC were measured in hepatocytes. (F, G) The fluorescence intensity of 2-NBDG in the hepatocyte. (H, I) The protein expression levels of p-IRS-1, IRS-1, p-Akt, and Akt were measured in hepatocytes. (E, G) Data are presented as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001 between every group, n = 3 samples per group.