TABLE 1.
Classification | Subclassification and characteristics |
---|---|
HSP90 | HSP90α is primarily found in the cytoplasm |
HSP90β is found in the mitochondria | |
HSP70 | Constitutive HSP70 (HSC70) is found in the cytoplasm |
Inducible HSP70 (HSP72) is produced in response to cellular stress | |
HSP60 | HSP60 (cytosolic) |
HSP60 (mitochondrial) | |
HSP40 | Constitutive HSP40 is found in the cytoplasm |
Inducible HSP40 is produced in response to cellular stress | |
Small HSPs | HSP27 is involved in the regulation of the actin cytoskeleton |
HSP20 is involved in protection against cellular damage |