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. 2024 Nov 5;15:1475998. doi: 10.3389/fphar.2024.1475998

TABLE 1.

Classification and characteristics of HSPs.

Classification Subclassification and characteristics
HSP90 HSP90α is primarily found in the cytoplasm
HSP90β is found in the mitochondria
HSP70 Constitutive HSP70 (HSC70) is found in the cytoplasm
Inducible HSP70 (HSP72) is produced in response to cellular stress
HSP60 HSP60 (cytosolic)
HSP60 (mitochondrial)
HSP40 Constitutive HSP40 is found in the cytoplasm
Inducible HSP40 is produced in response to cellular stress
Small HSPs HSP27 is involved in the regulation of the actin cytoskeleton
HSP20 is involved in protection against cellular damage