Table 2.

Study participant demographics and clinical data

Participant characteristics	Not Elevated (N= 1724)	Elevated (N= 517)	Total (N=2241)
Age, mean (SD)	68.30 (5.19)	70.42 (5.56)	68.79 (5.35)
Sex Female, n (%)	1088 (63.1%)	337 (65.2%)	1425 (63.6%)
Race, n (%)
American Indian or Alaskan Native	0 (0.0%)	0 (0.0%)	0 (0.0%)
Asian	15 (0.9%)	2 (0.4%)	17 (0.8%)
Black or African American	31 (1.8%)	5 (1.0%)	36 (1.6%)
Native Hawaiian or other Pacific Islander	0 (0.0%)	0 (0.0%)	0 (0.0%)
White	1658 (96.2%)	509 (98.5%)	2167 (96.7%)
Other	16 (0.9%)	1 (0.2%)	17 (0.8%)
Multiple	3 (0.2%)	0 (0.0%)	3 (0.1%)
Unknown	0 (0.0%)	0 (0.0%)	0 (0.0%)
Not reported	1 (0.1%)	0 (0.0%)	1 (0.0%)
Ethnicity, n (%)
Hispanic or Latino	73 (4.2%)	19 (3.7%)	92 (4.1%)
Not Hispanic or Latino	1637 (95.0%)	495 (95.7%)	2132 (95.1%)
Not reported	10 (0.6%)	1 (0.2%)	11 (0.5%)
Unknown	4 (0.2%)	2 (0.4%)	6 (0.3%)
Country, n (%)
AUS	243 (14.1%)	61 (11.8%)	304 (13.6%)
BEL	93 (5.4%)	23 (4.4%)	116 (5.2%)
CAN	6 (0.3%)	8 (1.5%)	14 (0.6%)
ESP	110 (6.4%)	25 (4.8%)	135 (6.0%)
FIN	20 (1.2%)	4 (0.8%)	24 (1.1%)
GBR	348 (20.2%)	64 (12.4%)	412 (18.4%)
ITA	20 (1.2%)	8 (1.5%)	28 (1.2%)
NLD	90 (5.2%)	25 (4.8%)	115 (5.1%)
SWE	19 (1.1%)	12 (2.3%)	31 (1.4%)
USA	775 (45.0%)	287 (55.5%)	1062 (47.4%)
APOE, n (%)
Carrier	426 (25.8%)	282 (55.7%)	708 (32.8%)
Non-carrier	1125 (74.2%)	224 (44.3%)	1449 (67.2%)
Missing	73	11	84
Family History of AD (Yes), n (%)	730 (42.3%)	250 (48.4%)	980 (43.7%)
Study partner type, n (%)
Spouse	1146 (67.4%)	339 (65.7%)	1485 (67.0%)
Adult child	165 (9.7%)	57 (11.0%)	222 (10.0%)
Other	390 (22.9%)	120 (23.3%)	510 (23.0%)
Missing	23	1	24
VPAI total score, mean (SD)	31.50 (6.67)	32.43 (6.60)	31.71 (6.67)