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. 2024 Nov 18;32(12):800. doi: 10.1007/s00520-024-08969-3

Table 3.

The association of device-measured and self-reported moderate-to-vigorous physical activity (MVPA) and device-measured sedentary time with health-related quality of life (HRQoL)

Global health status Physical functioning Role functioning Emotional functioning Cognitive functioning Social functioning Summary score Fatigue
β (95% CI) β (95% CI) β (95% CI) β (95% CI) β (95% CI) β (95% CI) β (95% CI) β (95% CI)
Device-measured MVPA in quartiles (h/week)a,b
  0–2.7 Ref Ref Ref Ref Ref Ref Ref Ref
  2.8–4.2 7.7 (2.9, 12.5)* 7.6 (3.9, 11.2)* 8.2 (1.0, 15.5)* 0.2 (− 5.6, 6.0)  − 0.8 (− 7.2, 5.7) 2.6 (− 4.1, 9.3) 2.8 (− 0.5, 6.1)  − 5.9 (− 12.4, 0.6)
  4.2–6.7 5.9 (0.8, 11.0)* 5.8 (1.9, 9.6)* 9.3 (1.6, 17.0)* 0.2 (− 5.9, 6.3)  − 0.6 (− 7.5, 6.2) 1.9 (− 5.1, 8.9) 3.7 (0.2, 7.1)*  − 7.8 (− 14.6, − 0.9)*
  ≥ 6.7 10.2 (5.1, 15.3)* 7.7 (3.8, 11.6)* 12.4 (4.7, 20.2)* 1.7 (− 4.5, 7.9) 0.6 (− 6.3, 7.5) 7.3 (0.2, 14.4)* 4.6 (1.1, 8.1)*  − 11.2 (− 18.1, − 4.2)*
  p-trend 0.001 0.001 0.003 0.60 0.83 0.06 0.01 0.002
Device-measured MVPA continuous (h/week)a,b
  1 unit increase 1.1 (0.4, 1.7)* 0.7 (0.2, 1.2)* 1.3 (0.3, 2.2)* 0.2 (− 0.5, 1.0)  − 0.1 (− 0.9, 0.8) 0.8 (− 0.1, 1.6) 0.5 (0.0, 0.9)*  − 1.3 (− 2.2, − 0.5)*
Device-measured MVPA in categories of WCRF/AICR recommendations (min/week)a,b,c
  < 150 Ref Ref Ref Ref Ref Ref Ref Ref
  ≥ 150 7.9 (3.6, 12.3)* 8.0 (4.7 (11.3)* 11.0 (4.5, 17.5)* 0.5 (− 4.8, 5.7)  − 0.0 (− 5.8, 5.8) 3.9 (− 2.1, 9.9) 3.6 (0.6, 6.5)*  − 7.5 (− 13.4, − 1.6)*
Self-reported MVPA in quartiles (h/week)a
  0–4.8 Ref Ref Ref Ref Ref Ref Ref Ref
  5.0–9.5 2.5 (− 2.1, 7.1) 5.5 (2.0, 9.0)* 7.8 (0.9, 14.7)* 0.4 (− 5.1, 5.8) 0.4 (− 5.7, 6.5) 3.3 (− 3.1, 9.6) 1.3 (− 1.8, 4.5)  − 5.8 (− 12.0, 0.3)
  9.5–16.8 6.6 (1.8, 11.3)* 7.6 (4.0, 11.2)* 9.0 (1.9, 16.1)* 0.5 (− 5.1, 6.2) 0.7 (− 5.6, 7.0) 3.6 (− 2.9, 10.1) 2.5 (− 0.7, 5.7)  − 6.2 (− 12.6, 0.1)
  ≥ 17.0 5.2 (0.5, 10.0)* 8.4 (4.8, 11.9)* 9.4 (2.4, 16.5)*  − 1.8 (− 7.4, 3.8) 1.6 (− 4.7, 7.8) 4.9 (− 1.5, 11.4) 2.3 (− 0.9, 5.5)  − 5.8 (− 12.2, 0.5)
  p-trend 0.01  < 0.001 0.01 0.55 0.61 0.15 0.12 0.09
Self-reported MVPA continuous (h/week)a
  1 unit increase 0.1 (− 0.0, 0.3) 0.2 (0.1, 0.3)* 0.3 (0.1, 0.5)*  − 0.1 (− 0.3, 0.1) 0.0 (− 0.2, 0.2) 0.1 (− 0.1, 0.3) 0.1 (− 0.0, 0.2)  − 0.1 (− 0.3, 0.1)
Self-reported MVPA in categories of WCRF/AICR recommendations (min/week)a,d
  < 150 Ref Ref Ref Ref Ref Ref Ref Ref
  ≥ 150 2.8 (− 2.4, 8.0) 4.4 (0.4, 8.3)* 4.9 (− 2.9, 12.6)  − 2.3 (− 8.4, 3.8)  − 1.2 (− 8.0, 5.6)  − 1.4 (− 8.5, 5.6) 0.2 (− 3.3, 3.7)  − 2.3 (− 9.3, 4.6)
Device-measured sedentary time in quartiles (h/day)a,e
  ≥ 11.4 Ref Ref Ref Ref Ref Ref Ref Ref
  10.2–11.4  − 1.4 (− 6.1, 3.3) 0.2 (− 3.4, 3.7)  − 6.1 (− 13.1, 0.9)  − 4.0 (− 9.6, 1.6)  − 5.7 (− 11.9, 0.5)  − 5.8 (− 12.3, 0.6)  − 1.9 (− 5.1, 1.3) 4.4 (− 1.9, 10.6)
  8.8–10.2 0.8 (− 3.9, 5.6) 3.8 (0.2, 7.4)* 0.7 (− 6.4, 7.8)  − 1.7 (− 7.4, 3.9)  − 3.0 (− 9.3, 3.3)  − 0.1 (− 6.5, 6.4) 1.4 (− 1.9, 4.6)  − 0.5 (− 6.8, 5.8)
  0–8.8 1.3 (− 3.7, 6.3) 4.6 (0.8, 8.5)*  − 2.3 (− 9.8, 5.2)  − 4.9 (− 10.9, 1.1)  − 3.8 (− 10.5, 2.9)  − 2.2 (− 9.0, 4.7)  − 0.9 (− 4.3, 2.6) 1.3 (− 5.4, 8.0)
  p-trend 0.46 0.005 1.00 0.20 0.40 0.94 0.89 0.93
Device-measured sedentary time continuous (h/day)a,e
  1 unit decrease 0.5 (− 0.6, 1.5) 1.2 (0.4, 2.0)* 0.5 (− 1.1, 2.1) 0.7 (− 1.9, 0.6)  − 0.3 (− 1.7, 1.0) 0.2 (− 1.2, 1.7) 0.2 (− 0.5, 0.9)  − 0.2 (− 1.6, 1.2)

*p < 0.05

aModel is adjusted for age (years), sex (male, female), BMI (kg/m2), comorbidities (0, 1, ≥ 2), tumor stage (I, II, III), smoking status (never, former, current), education level (low, medium, high), and mobility limitation (yes, no)

bModel for device-measured MVPA is also adjusted for sedentary time (h/day)

c0–150 (n = 77), ≥ 150 (n = 264)

d0–150 (n = 40); ≥ 150 (n = 300)

eModel for sedentary time is also adjusted for MVPA (h/week)