Figure 5.

Proposed algorithm for the use of predniso(lo)ne with mycophenolate mofetil (MMF) in treatment-naïve patients with AIH

*In case of flares or relapses, predniso(lo)ne should be increased or restarted, respectively, up to the dose that achieved initial CBR, and then tapered, either by decreasing the predniso(lo)ne tapering dose by half with the same interval time, or by a twofold increase of the interval time

AIH, autoimmune hepatitis; CBR, complete biochemical response; AST, aspartate aminotransferase; ALT, alanine aminotransferase; IgG, immunoglobulin G