TABLE 2.
Baseline characteristics of the enrolled participants.
| Variable | HCC group (n = 229) | CHB group (n = 296) | HC group (n = 96) |
|---|---|---|---|
| Age (years) | 56 (49–63) | 48 (38–55) | 40 (32–55.75) |
| Male, n (%) | 106 (79.7) | 119 (72.6) | 11 (42.3) |
| ALT (U/L) | 32.00 (21.00–47.00) | 41.00 (25.50–104.50) | 15.00 (10.00–23.00) |
| AST (U/L) | 36.00 (26.00–59.00) | 44.00 (25.00–99.00) | 21.00 (15.00–41.50) |
| TBIL (μmol/L) | 17.25 (12.93–25.35) | 17.00 (11.90–39.45) | 13.90 (8.40–33.80) |
| ALB (g/L) | 40.90 (36.40–44.15) | 41.40 (33.60–46.40) | 46.95 (45.70–48.88) |
| PLT (10 ^ 9/L) | 127 (88.50–186.00) | 148.5 (80.00–201.00) | 238 (210.00–290.00) |
| PT-INR | 12.7 (11.8–13.55) | 12.5 (11.6–14.98) | NA |
| PTA (%) | 86 (75–96) | 87 (68–100) | NA |
| AFP (ng/mL) | 31.40 (5.513–753.30) | 6.47 (2.72–62.86) | NA |
| HBV-DNA (+), n (%) | 122 (53.3) | 214 (72.3) | NA |
| HBeAg (+), n (%) | 218 (95.2) | 291 (98.3) | NA |
| Encephalopathy (%) | 68 (29.69) | 131 (44.26) | NA |
| Ascites (%) | 11 (4.80) | 26 (8.78) | NA |
Quantitative variables are expressed as the median (25th percentile; 75th percentile). Categorical variables are expressed as numbers (%). HCC, hepatocellular carcinoma; CHB, chronic hepatitis B; HC, healthy control; HBV, hepatitis B virus; AFP, alpha-fetoprotein; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALB, albumin; TBIL, total bilirubin; INR, international normalized ratio; PTA, prothrombin time activity; HBeAg, hepatitis B e surface antigen; NA, not available.