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Diagnostic values of Mex3a methylation level, Mex3a mRNA level, and the combined determination with AFP for distinguishing HBV-associated HCC from CHB in the verification set.
| Parameter | Sensitivity | Specificity | Youden index |
|---|---|---|---|
| AFP | 64.1 | 72.1 | 0.362 |
| Mex3a mRNA level + Mex3a PMR + AFP | 69.2 | 93.4 | 0.627 |
