Figure 1.

PM_2.5 exposure during the entire pregnancy (each SD) was associated with the neurodevelopment of children. (A) Association between prenatal PM_2.5 exposure and ASQ scores at 2, 6, 12, and 24 months of age. (B) Association of prenatal PM_2.5 exposure and ASQ scores at 2 months of age in a two-pollutant model. (C) Association of prenatal PM_2.5 exposure and SDD at 2, 6, 12, and 24 months of age. (D) Association of prenatal PM_2.5 exposure and SDD at 2 months of age in a two-pollutant model. Results were presented as calculated values β, odds ratio (OR), and 95% confidence intervals (CI), and the highlighted associations in red are at P value <0.05. These models were adjusted for confounders of parental characteristics (parity, maternal age, maternal pregravid BMI, maternal physical activity, maternal educational level, annual family income, pregnancy syndrome, passive smoking status, season of conception, delivery mode, paternal age, premature birth, gestational weight gain (GWG), temperature, and relative humidity) and child characteristics (child age at ASQ test, birthweight, feeding patterns, and child sex).Abbreviations: BMI, body mass index; ASQ, Ages and Stages Questionnaire; SDD, suspected developmental delay at followup point.