Figure 5.

Differential KEGG functional pathways and genus related to PM_2.5 exposure during the entire pregnancy. (A) Differential KEGG functional pathways related to prenatal PM_2.5 exposure. The association of KEGG functional pathways (KEGG level 3, using phylogenetic investigation of communities by reconstruction of unobserved states (PICRUSt) data sets) and gestational PM_2.5 exposure was assessed by Multivariate Analysis by Linear Models (q-value <0.25 was considered significant). (B) Association between seven differentially abundant taxa and PM_2.5-related KEGG functional pathways. The “black hole” indicates P value >0.05.