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. 2024 Nov 19;12(6):e70034. doi: 10.1002/prp2.70034

TABLE 3.

Results of the ablation study.

Excluded embedding Gene/protein embedding by the LLM Disease embedding by the LLM Disease embedding by the KGE Gene/protein embedding by the KGE
AUC 0.9653 ± 0.0002 0.9633 ± 0.0002 0.9520 ± 0.0005 0.8794 ± 0.0031
AUPR 0.9455 ± 0.0008 0.9404 ± 0.0004 0.9261 ± 0.0008 0.8236 ± 0.0052
F1 score 0.8774 ± 0.0026 0.8739 ± 0.0034 0.8552 ± 0.0018 0.7432 ± 0.0032
Accuracy 0.9051 ± 0.0032 0.9018 ± 0.0047 0.8903 ± 0.0016 0.8110 ± 0.0044
Recall 0.9096 ± 0.0115 0.9105 ± 0.0203 0.8672 ± 0.0098 0.7325 ± 0.0097
Precision 0.8477 ± 0.0139 0.8408 ± 0.0218 0.8437 ± 0.0088 0.7545 ± 0.0132
Specificity 0.9023 ± 0.0116 0.8966 ± 0.0190 0.9041 ± 0.0072 0.8577 ± 0.0119

Note: The results were reported as average ± standard deviation.

Abbreviations: AUC, area under the receiver operating characteristic curve; AUPR, area under the precision‐recall curve; GNN, graph neural network; LLM, large language model.