Table 1.
Baseline characteristics of male AMI patients in total and by three 6-year time periods: categorical variables are displayed as total numbers (%).
| Total sample: n = 8095 | 2000–2005 n = 2849 | 2006–2011: n = 2632 | 2012–2017: n = 2614 | p-Value | n | |
|---|---|---|---|---|---|---|
| Age at AMI | 60.39 (9.62) | 60.33 (9.67) | 60.29 (9.79) | 60.54 (9.40) | 0.608 | 8095 |
| Total deaths | 2727 (33.7%) | 1442 (50.6%) | 831 (31.6%) | 454 (17.4%) | <0.001 | 8095 |
| 28-days-mortality | 471 (5.8%) | 199 (7.0%) | 142 (5.4%) | 130 (5.0%) | 0.003 | 8095 |
| CVD-mortality | 1533 (18.9%) | 826 (29.0%) | 454 (17.2%) | 253 (9.7%) | <0.001 | 8095 |
| Ischemic heart disease-mortality | 1218 (15.0%) | 665 (23.3%) | 348 (13.2%) | 205 (7.8%) | <0.001 | 8095 |
| Cancer-mortality | 507 (6.3%) | 271 (9.5%) | 149 (5.7%) | 87 (3.3%) | <0.001 | 8095 |
| Type of infarction | 0.073 | 8095 | ||||
| STEMI | 3062 (37.8%) | 1054 (37.0%) | 1006 (38.2%) | 1002 (38.3%) | ||
| NSTEMI | 4158 (51.4%) | 1455 (51.1%) | 1382 (52.5%) | 1321 (50.5%) | ||
| Bundle branch block | 546 (6.7%) | 213 (7.5%) | 155 (5.9%) | 178 (6.8%) | ||
| Not defined | 329 (4.1%) | 127 (4.5%) | 89 (3.4%) | 113 (4.3%) | ||
| Invasive treatment | ||||||
| CABG | 1289 (15.9%) | 525 (18.4%) | 391 (14.9%) | 373 (14.3%) | <0.001 | 8095 |
| PCI | 5629 (69.5%) | 1664 (58.4%) | 1931 (73.4%) | 2034 (77.8%) | <0.001 | 8095 |
| Prehospital time in minutes | 152.00 (80.00–480.00) | 156.00 (82.00–462.00) | 145.00 (82.00–430.50) | 154.00 (76.00–546.00) | 0.813 | 6177 |
| BMI (kg/m2) | 27.69 (4.34) | 27.35 (3.92) | 27.84 (4.38) | 27.89 (4.69) | <0.001 | 7469 |
| Hypertension | 5944 (73.4%) | 2069 (72.6%) | 2006 (76.2%) | 1869 (71.5%) | <0.001 | 8095 |
| Diabetes mellitus | 2422 (29.9%) | 847 (29.7%) | 849 (32.3%) | 726 (27.8%) | <0.001 | 8095 |
| Previous infarction | <0.001 | 8095 | ||||
| Yes | 808 (10.0%) | 439 (15.4%) | 231 (8.8%) | 138 (5.3%) | ||
| No | 7275 (89.9%) | 2400 (84.2%) | 2400 (91.2%) | 2475 (94.7%) | ||
| No information | 12 (0.1%) | 10 (0.4%) | 1 (0.0%) | 1 (0.0%) | ||
| Previous stroke | <0.001 | 8095 | ||||
| Yes | 571 (7.1%) | 198 (6.9%) | 176 (6.7%) | 197 (7.5%) | ||
| No | 6984 (86.3%) | 2264 (79.5%) | 2327 (88.4%) | 2393 (91.5%) | ||
| No information | 540 (6.7%) | 387 (13.6%) | 129 (4.9%) | 24 (1.0%) | ||
| Smoking status | <0.001 | 8095 | ||||
| Current smoker | 3029 (37.4%) | 969 (34.0%) | 995 (37.8%) | 1065 (40.7%) | ||
| Ex-smoker | 2673 (33.0%) | 948 (33.3%) | 873 (33.2%) | 852 (32.6%) | ||
| Never-smoker | 1679 (20.7%) | 575 (20.2%) | 542 (20.6%) | 562 (21.5%) | ||
| No information | 714 (8.8%) | 357 (12.5%) | 222 (8.4%) | 135 (5.2%) | ||
| LVEF | <0.001 | 8095 | ||||
| ≤30% | 460 (5.7%) | 133 (4.7%) | 121 (4.6%) | 206 (7.9%) | ||
| >30% | 5636 (69.6%) | 1641 (57.6%) | 1772 (67.3%) | 2223 (85.0%) | ||
| No information | 1999 (24.7%) | 1075 (37.7%) | 739 (28.1%) | 185 (7.1%) | ||
| Laboratory values | ||||||
| Admission troponin I (ng/ml) | 0.60 (0.11–3.92) | 0.57 (0.12–4.08) | 0.63 (0.11–3.80) | 0.56 (0.10–4.64) | 0.984 | 5086 |
| Peak CKMB levels (U/l) | 54.00 (23.00–143.00) | 37.00 (14.00–94.00) | 56.00 (24.00–160.00) | 78.00 (35.00–188.00) | <0.001 | 7237 |
| Admission CRP (mg/dl) | 0.45 (0.23–1.30) | 0.46 (0.19–1.31) | 0.46 (0.29–1.35) | 0.41 (0.22–1.20) | <0.001 | 7480 |
| Peak glucose (mg/dl) | 148.00 (121.00–199.00) | 155.00 (128.00–215.00) | 148.00 (122.00–193.00) | 139.00 (115.25–184.75) | <0.001 | 7873 |
| eGFR (mL/min/1.73 m2) | 78.93 (62.09–92.98) | — | 76.45 (59.96–91.64) | 81.30 (64.87–93.82) | <0.001 | 5114 |
LVEF: left ventricular ejection fraction.
Numeric data is presented as mean (SD) or median (IQR).