Survival analysis of sTIL. OS benefit of sTILHigh in DBDCs with (A) lower disease stages (stages I and II) and (B) higher disease stages (stages III and IV). RFS benefit of sTILHigh in DBDCs with (C) lower disease stages (stages I and II) and (D) higher disease stages (stages III and IV). DBDC, distal extrahepatic bile duct carcinoma; OS, overall survival; RFS, recurrence-free survival; sTIL, stromal tumor-infiltrating lymphocyte; sTILHigh, high level of sTIL density.