Table 1.

Case Reports Documenting CLL and a Concurrent Diagnosis of APL.

Reference	Patient age at APL diagnosis (y)	Therapy-related AML status	CLL status at emergence of APL	Treatment of APL	Outcome	CLL status at last follow-up
Molero et al. [10]	68	2 y post prostate cancer radiotherapy	40% marrow involvement	Idarubicin and all-trans-retinoic acid	Complete remission of APL 1 y later	Persistent disease, extent of disease not reported
Su et al. [9]	52	De novo	Peripheral blood lymphocytosis	All-trans-retinoic acid and hydroxyurea	Early death from hypoxic respiratory failure and disseminated intravascular coagulation	-
Current study	71	De novo	Minimal residual CLL (0.07%)	All-trans-retinoic acid and arsenic trioxide	Complete remission of APL 1 y later	Persistent minimal residual CLL (0.17%)

Note. AML = acute myeloid leukemia; APL = acute promyelocytic leukemia; CLL = chronic lymphocytic leukemia; y = year.