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Cell-distending effects of Cytolethal Distending Toxin and colibactin. HeLa cells were treated with purified E. coli CDT (CDTwt) or with CDT mutated on CdtB-conserved histidine (H153A) (CDTm) or infected with E. coli producing or not colibactin (E. coli pks+ and pks–). Cells were stained with methylene blue 3 days after the treatment. Bar represents 100 µm.
