Figure 4.

Structural conservation of the catalytic cores of E. coli and S. Typhi CdtB and DNase I. E. coli CdtB (Protein Data Bank [PDB] 2F1N, light blue), S. Typhi CdtB (PDB 4K6L, purple) aligned with DNase I (light grey) complexed with target DNA (PDB 1DNK, green). The main catalytic residues D211, H136, and H243 are highlighted in red.