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| IC50 (µM) ± SEM* | ||
|---|---|---|
| Compound no. | L. major DHFR | L. major PTR1 |
| 4g | 8.09 ± 0.01 | 0.58 ± 0.05 |
| 20a | 2.63 ± 0.01 | 15.86 ± 0.01 |
| 20b | 1.14 ± 0.01 | 19.89 ± 0.01 |
| MTX | 0.004 ± 0.000 | 0.173 ± 0.008 |
SEM* = standard error of the mean (n = 3).
