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. 2024 Nov 19;19(11):e0304937. doi: 10.1371/journal.pone.0304937

Table 2. Multivariate COX models and Fine-Gray models for survival analysis.

COX-CSS COX-OS FGM-CSS
no-ACRT HR (95% CI) p HR (95% CI) p HR (95% CI) p
Model 1 Ref 1.111 (0.962–1.283) 0.154 1.010 (0.885–1.153) 0.883 1.135 (0.984–1.308) 0.082
Model 2 Ref 1.105 (0.957–1.277) 0.174 1.009 (0.884–1.152) 0.891 1.127 (0.977–1.299) 0.100
Model 3 Ref 1.102 (0.954–1.274) 0.187 1.010 (0.884–1.154) 0.882 1.124 (0.975–1.297) 0.110
Model 4 Ref 1.097 (0.949–1.268) 0.211 1.007 (0.881–1.150) 0.920 1.125 (0.975–1.297) 0.110
Model 5 Ref 1.087 (0.940–1.257) 0.259 0.998 (0.874–1.141) 0.982 1.118 (0.969–1.290) 0.130

Model 1: no adjustment

Model 2: adjusted for age, gender, year of diagnosis

Model 3: model 2 + T classification, N classification, TNM stage

Model 4: model 3 + tumor histology, histological grade

Model 5: model 4 + race, marital status.

no-ACRT group was set as a reference.

ACRT, adjuvant chemotherapy or radiotherapy; Ref, reference; CSS, cancer-specific survival; OS, overall survival; FGM: Fine-Gray model; HR, hazard ratio; CI, confidence interval.