Table 2. Diagnosis method for NCJDRSU criteria for sporadic CJD .

NCJDRSU: national CJD research and surveillance unit [11], CJD: Creutzfeldt-Jakob disease

I, II, III, IV are criteria listed in Table 1.

Criteria	Definite	Probable	Possible
Diagnosis method	Progressive neurological syndrome and neuropathologically or immunocytochemically or biochemically confirmed	(a) I+2 of II and III; (b) I+2 of II and IV; (c) I+2 of II and positive I4-3-3; (d) progressive neurological syndrome and positive RT-QuIC in CSF or other tissues	I+2 of II+duration <2 years