Table III.
Metabolic parameters on days 1, 3 and 5 in Mirasol-treated platelets stored in PAS and plasma
| Parameter/Day | Mirasol-median (IQR) | p-value | |
|---|---|---|---|
| PAS | Plasma | ||
| Concentration (10 3 /uL), 1 | 119 (86.5–119) | 112.4 (101–113) | 0.91 |
| Concentration (10 3 /uL), 3 | 115 (109.5–115) | 115.5 (107.3–126.5) | 0.45 |
| Concentration (10 3 /uL), 5 | 85.5 (85.5–103) | 115 (111.3–121.8) | 0.046 |
| p-value | 0.61 | 0.41 | |
| pH, 1 | 7.15 (7.11–7.17) | 7.10 (7.10–7.30) | 0.82 |
| pH, 3 | 6.93 (6.87–6.99) | 6.95 (6.90–7.01) | 0.62 |
| pH, 5 | 6.80 (6.80–6.87) | 6.50 (6.50–6.70) | 0.007 |
| p-value | 0.003 | 0.002 | |
| pO 2 (mmHg), 1 | 72 (48–72) | 49.7 (21.3–63.5) | 0.46 |
| pO 2 (mmHg), 3 | 94 (90–104) | 41.9 (38.4–55.2) | 0.027 |
| pO 2 (mmHg), 5 | 109 (107–123) | 56.2 (44.7–110.6) | 0.17 |
| p-value | 0.18 | 0.67 | |
| pCO 2 (mmHg), 1 | 15 (14–16) | 42.3 (27.9–45.9) | 0.009 |
| pCO 2 (mmHg), 3 | 12 (10–13) | 23.3 (21.9–26.4) | 0.013 |
| pCO 2 (mmHg), 5 | 10 (8–11) | 17.5 (15–17.8) | 0.008 |
| p-value | 0.021 | 0.010 | |
| Glucose(mg/dL), 1 | 88 (84–94) | 276 (257–291) | 0.009 |
| Glucose(mg/dL), 3 | 27 (20–31) | 216 (195.5–221) | 0.014 |
| Glucose(mg/dL), 5 | 0 (0–0) | 118 (93–136) | 0.005 |
| p-value | 0.002 | 0.003 | |
| Lactate(mmol/L), 1 | 1.4 (1.3–1.4) | 2.4 (1.8–2.5) | 0.058 |
| Lactate(mmol/L), 3 | 8.1 (8.1–10.4) | 10.7 (10.5–11.0) | 0.14 |
| Lactate(mmol/L), 5 | 12.6 (12.2–12.9) | 17.8 (17.7–18.0) | 0.009 |
| p-value | 0.003 | 0.003 | |
| LDH(IU/L), 1 | 44 (36–61) | 75 (59–88) | 0.29 |
| LDH(IU/L), 3 | 59 (55–78) | 73 (71–129) | 0.29 |
| LDH(IU/L), 5 | 85 (78–290) | 116 (103–153) | 0.65 |
| p-value | 0.09 | 0.17 | |
p-values in bold stand for statistically significant results (p<0.05). IQR: interquartile range; LDH: lactate dehydrogenase.