Table IV.
Hemostatic parameters on days 1, 3 and 5 in Mirasol-treated platelets stored in PAS and plasma
| Parameter/Day | Mirasol-median (IQR) | p-value | |
|---|---|---|---|
| PAS | Plasma | ||
| LTA ADP (%), 1 | 21 (20–36) | 27 (27–47) | 0.40 |
| LTA ADP (%), 3 | 7 (5–8) | 19 (13–25.5) | 0.10 |
| LTA ADP (%), 5 | 3 (0–4) | 11 (11–13) | 0.045 |
| p-value | 0.008 | 0.015 | |
| CT EXTEM (sec), 1 | 77 (69–85) | 53 (47–61) | 0.07 |
| CT EXTEM (sec), 3 | 65 (63–77) | 65.5 (50.5–68.5) | 0.71 |
| CT EXTEM (sec), 5 | 70 (54–79) | 60 (43–70) | 0.29 |
| p-value | 0.62 | 0.95 | |
| CFT EXTEM (sec), 1 | 63 (48–84) | 49 (47–51) | 0.20 |
| CFT EXTEM (sec), 3 | 69 (58–113) | 53.5 (51–64) | 0.14 |
| CFT EXTEM (sec), 5 | 109 (107–1094) | 57 (53–57) | 0.046 |
| p-value | 0.08 | 0.08 | |
| A10 EXTEM (mm), 1 | 56 (47–57) | 62 (60–63) | 0.021 |
| A10 EXTEM (mm), 3 | 31 (29–36) | 38.5 (33.5–40.5) | 0.38 |
| A10 EXTEM (mm), 5 | 20 (19–25) | 27 (23–31) | 0.17 |
| p-value | 0.004 | 0.005 | |
| MCF EXTEM (mm), 1 | 61 (50–61) | 66 (64–67) | 0.011 |
| MCF EXTEM (mm), 3 | 35 (30–41) | 41 (38.5–42.5) | 0.21 |
| MCF EXTEM (mm), 5 | 20 (19–26) | 34 (30–37) | 0.11 |
| p-value | 0.004 | 0.007 | |
| MCE EXTEM, 1 | 156 (102–157) | 191 (178–200) | 0.016 |
| MCE EXTEM, 3 | 53 (43–70) | 70.5 (62.5–75) | 0.17 |
| MCE EXTEM, 5 | 26 (24–35) | 52 (43–58) | 0.11 |
| p-value | 0.004 | 0.007 | |
p-values in bold stand for statistically significant results (p<0.05). IQR: interquartile range; LTA: light transmission aggregometry; EPI: epinephrine; ADP: adenosine diphosphate; CT: clotting time; CFT: clot formation time; A10: amplitude 10 min after CT; A20: amplitude 20 min after CT; A30: amplitude 30 min after CT; MCF: maximum clot firmness; LI60:lysis index at 60 minutes; MCE: maximum clot elasticity.