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. 2024 Nov 6;15:1502354. doi: 10.3389/fphar.2024.1502354

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Copyright © 2024 Shen, Yuan, Li, Ling, Wang, Gao, Wang, Li, Lai and Jin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of BBR on Notch1 signaling in myocardial tissue of sepsis rats (A1) Western blot of Notch1and NICD in rats in each group. (A2) Notch1 and NICD proteins expression level in rats in each group. (B) Hes1 gene expression level in rats in each group. (C) Hes2 gene expression levels in rats in each group. (D) Hey1 gene expression level in rats in each group. (E) Hey2 gene expression level in rats in each group. (F) Notch1 gene expression level in rats in each group. *P < 0.05, **P < 0.01 vs Sham group; #P < 0.05, ##P < 0.01 vs CLP group; N = 6, biological replication.