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Knockdown of SFXN4 and SQOR affected osteosarcoma growth in vivo. 143B cells were transfected with lentivirus expressing either shNC, shSFXN4, or shSQOR. (A) Knockdown of SFXN4 significantly inhibited tumor growth. (B, C) Volume changes and weight of shNC and shSFXN4 tumors. (D) Knockdown of SQOR promoted tumor growth. (E, F) Volume changes and weight of shNC and shSQOR tumors. **p < 0.01.
