Figure 1.

Differential genes between sciatica patients and healthy individuals in GSE124272 and GSE150408 datasets

(A and B) Volcano plot displaying differential genes in GSE124272 and GSE150408 between sciatica patients and healthy individuals (independent-samples t test, mean ± SD).

(C) Venn diagram showing 3 commonly upregulated genes in both datasets.

(D) Venn diagram displaying 7 commonly downregulated genes in both datasets.

(E and F) Heatmap presenting the expression of intersecting genes in GSE124272 and GSE150408.

(G–J) Violin plot showing NADK2 expression in the blood of patients with migraine, fibromyalgia, clavicular cortical hyperostosis, and complex regional pain syndrome compared to healthy individuals (independent-samples t test, mean ± SD).