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. 2024 Oct 28;27(11):111265. doi: 10.1016/j.isci.2024.111265

Table 2.

Top significantly regulated miRNA candidates and their target mRNAs within the HBMEC1.5

miRNA-ID Fold change Target mRNA mRNA fold change Context++ score percentile Predicted relative KD
hsa-miR-154-5p −8,157 JAM3 15,516 99 −4.482
hsa-miR-99a-5p 7,437 CLDN11 174,121 95 −4.377
hsa-miR-625-5p −8,157 CLDN11 174,121 99 −2.957
hsa-miR-92b-3p 76,008 CLDN11 174,121 99 −5.156
hsa-miR-493-5p −24,471 CXCL8 431,368 91 N/A
hsa-miR-889-3p −4,894 CXCL8 431,368 99 −5.047
hsa-miR-654-5p −12,236 CXCL16 68,367 51 −2.424
hsa-miR-193a-5p −24,471 PVR 191,583 76 −2.675
hsa-miR-431-5p −6,118 ICAM1 746,207 94 −4.882
hsa-miR-4448 2,738 ICAM1 746,207 97 N/A
hsa-miR-3187-3p −24,471 CXCL1 10,404 99 −5.019
hsa-miR-155-5p 2,493 ACTA1 −445,009 99 −5.133
hsa-miR-214-3p −4,894 ATF2 −3,907 97 −4.449
hsa-miR-3613-5p −24,471 ATF2 −3,907 98 −5.739
hsa-miR-376c-5p −24,471 ATF2 −3,907 97 N/A
hsa-miR-625-5p −8,157 ATP2A1 −20,989 81 −1.954
hsa-miR-214-3p −4,894 ATP2A2 −3,408 92 −4.295
hsa-miR-329-3p −12,236 ATP2A2 −3,408 N/A N/A
hsa-miR-625-5p −8,157 ATP2B4 167,419 61 −2.140
hsa-miR-654-5p −12,236 CABIN1 −2,257 96 −3.977
hsa-miR-197-3p −2,039 CACNG8 11,356 84 −3.025
hsa-miR-454-3p −24,471 CALM2 −3,380 99 −4.616
hsa-miR-193b-3p −12,236 CALM2 −3,380 N/A N/A
hsa-miR-660-5p −24,471 CALM2 −3,380 N/A N/A
hsa-miR-204-5p 85,448 CAMK1 −2,832 99 −4.840
hsa-miR-3130-5p −24,471 CHRNA7 44,331 86 N/A
hsa-miR-485-3p −12,236 CHRNA7 44,331 85 −3.448
hsa-miR-193b-3p −12,236 CHRNB1 −8,790 97 −4.273
hsa-miR-455-3p −3,496 CHRNB1 −8,790 N/A N/A
hsa-miR-455-3p −3,496 HDAC2 −2,396 N/A N/A
hsa-miR-454-3p −24,471 MAPK1 −2,443 96 −4.184
hsa-miR-493-5p −24,471 MEF2C −4,689 77 −3.196
hsa-miR-501-5p −24,471 MEF2C −4,689 97 N/A
hsa-miR-99a-5p 7,437 PPP3CA −10,105 94 −4.828
hsa-miR-376a-3p −4,894 PRKACB −5,403 98 −4.086
hsa-miR-496 −8,157 PRKACB −5,403 N/A N/A
hsa-miR-654-5p −12,236 PRKAR2A 2,257 80 −3.724
hsa-miR-455-3p −3,496 PRKD3 −2,904 N/A N/A
hsa-miR-149-5p 16,673 RAP1A −2,549 99 −4.440
hsa-miR-337-3p 1,962 RAP1A −2,549 99 −4.873
hsa-miR-149-5p 16,673 RAP1B −3,972 97 −2.479
hsa-miR-92b-3p 76,008 RAP1B −3,972 97 −4.116
hsa-miR-485-3p −12,236 RAP2A 2,401 94 −3.390
hsa-miR-487a-5p −8,157 RAP2A 2,401 95 N/A