REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Alexa Fluor 488	Thermo Fisher Scientific	#A28175
α human CD29 (integrin beta1)	Biolegend, San Diego, USA	–
Chemicals
RPMI 1640	Applichem	A1538,9010
Hypoxanthine	Sigma	H9636-56
Gelatin from porcine skin-175 g bloom type A	Sigma	G2625
Complete human endothelial cell kit	Cell Biologics®	#H1168
Microvascular endothelial cell growth medium	Provitro®	#2010102
Experimental models: Cell lines
HBMEC (brain ECs)	Cell Biologics	# H-6023
HMVEC-L (lung ECs)	Provitro®	#1210144
Human Serum	Human Serum (A+) Interstate Blood Bank, Inc (Memphis, USA).	–
Experimental models: Organisms/strains
IT4 (FCR3S1.2)	In August 1976, 1 mL of patient blood (MRCL, Fajara-Gambia, West Africa) was diluted in 10 mL RPMI 1640 and 10% FCS and shipped on wet ice to New York, NY, USA. Parasites were cultured directly in continuous cultures using the Petri-dish-candle jar technique (Jensen und Trager, 1978), resulting in cell lines FCR3 or IT4. Although the cells were suspected to be mixed with another Brazilian isolate, the cells only contained one genome. This isolate was supplied by Mo Klinkert, BNITM, Hamburg.	–
Software and algorithms
NanoSight Software	(NTA3 0064)	–
Agilent 2100® bioanalyzer software	–	Santa Clara, USA
CLC genomics work bench	version 21	Qiagen, Aarhus
IPA	–	Qiagen, Aarhus
Graphpad Prism	Version 9.4.1	San Diego, California
Kits
QUbit TM Protein Assay Kit	ThermoFisher Scientific, Waltham, USA	#Q33211
Ultrafiltration units 100,000 MWCO PES	Sartorius, Göttingen, Germany
miRNeasy mini-Kit	Qiagen, Hilden, Germany
Agilent 2100® bioanalyzer Pico-Kit	Agilent
QIAseq Standard mRNA Select Kit (96)	Qiagen	#180775
NextSeq 500/550 Mid Output Kit v.25 (150 Cycles)	Illumina	#20024904
Data deposit
NCBI	PRJNA1066103