TABLE 2.
Characteristics of women who were referred for prenatal ES.
| Accepted by testing laboratory (n = 308) a | Not accepted by GLH (n = 101) n (%) | Total (N = 409) n (%) | ||
|---|---|---|---|---|
| Proceeded with prenatal ES (n = 241) n (%) | Not proceeded with prenatal ES (n = 67) n (%) | |||
| Maternal age, years | ||||
| <25 | 35 (14.5) | 4 (6.3) | 11 (12.6) | 50 (12.8) |
| 25-<30 | 61 (25.3) | 20 (31.2) | 16 (18.4) | 97 (24.7) |
| 30-<35 | 85 (35.3) | 19 (29.7) | 27 (31.0) | 131 (33.4) |
| ≥35 | 60 (24.9) | 21 (32.8) | 33 (37.9) | 114 (29.1) |
| Missing | 0 | 3 | 14 | 17 |
| Maternal Ethnicity | ||||
| White | 153 (74.6) | 14 (87.5) | 14 (77.8) | 181 (75.7) |
| Black, Asian, and Other Minority | 52 (25.4) | 2 (12.4) | 4 (22.2) | 58 (24.3) |
| Missing | 36 | 51 | 83 | 170 |
| Index of Multiple Deprivation | ||||
| Quintile 1 (Most deprived) | 54 (23.8) | 14 (26.4) | 19 (25.7) | 87 (24.6) |
| Quintile 2 | 48 (21.2) | 9 (17.0) | 16 (21.6) | 73 (20.6) |
| Quintile 3 | 47 (20.7) | 8 (15.1) | 18 (24.3) | 73 (20.6) |
| Quintile 4 | 41 (18.1) | 12 (22.6) | 11 (14.9) | 64 (18.1) |
| Quintile 5 (Least deprived) | 37 (16.3) | 10 (18.9) | 10 (13.5) | 57 (16.1) |
| Missing | 14 | 14 | 27 | 55 |
a
413 women were referred but 4 women requested to withdraw before approval decision.
p-values for comparison of characteristics for accepted vs. not accepted and for proceeded vs. no proceeded are greater than 0.05.
n (%) for women who proceeded with pES are different from Tables 4, 6, and 8 because data used to construct this table were obtained from GLHs alone as referral data were not available in the linked data due to data restrictions.
Abbreviations: ES: exome sequencing, GLH: genomic laboratory hub.