Table 1.
Characteristics of CHAPS participants included in the analysis, overall and by study site.
| Characteristic | All participants N=139 |
South Africa N=68 |
Uganda N=71 |
p-value1 |
|---|---|---|---|---|
| Sex, male | 139 (100%) | 68 (100%) | 71 (100%) | 1.00 |
| Age in years, median (interquartile range) [range] | 19 (16-21) [13-24] |
20 (16-22) [13-24] |
19 (16-21) [13-23] |
0.51 |
| BMI, mean (SD) | 20.7 (2.9) | 20.8 (3.6) | 20.6 (2.0) | 0.68 |
| Chlamydia positive | 6 (4%) | 2 (3%) | 4 (6%) | 0.45 |
| Trial arm | 1.00 | |||
| Control | 16 (12%) | 8 (12%) | 8 (11%) | |
| FTC-TDF, 2 tablets, 5 hours | 16 (12%) | 8 (12%) | 8 (11%) | |
| FTC-TDF, 2 + 1 tablets, 5 hours | 16 (12%) | 8 (12%) | 8 (11%) | |
| FTC-TDF, 2 tablets, 21 hours | 16 (12%) | 8 (12%) | 8 (11%) | |
| FTC-TDF, 2 + 1 tablets, 21 hours | 15 (11%) | 7 (10%) | 8 (11%) | |
| FTC-TAF, 2 tablets, 5 hours | 14 (10%) | 7 (10%) | 7 (10%) | |
| FTC-TAF, 2 + 1 tablets, 5 hours | 15 (11%) | 7 (10%) | 8 (11%) | |
| FTC-TAF, 2 tablets, 21 hours | 16 (12%) | 8 (12%) | 8 (11%) | |
| FTC-TAF, 2 + 1 tablets, 21 hours | 15 (11%) | 7 (10%) | 8 (11%) |
1P-value for difference in distribution of characteristics between South Africa and Uganda participants: Wilcoxon rank-sum test used to compare age (as non-normally distributed), t-test used to compare BMI, chi-squared test used to compare sex, chlamydia result and trial arm.