Table 3.
Adjusted HRs for Ventricular Tachycardia and Sudden Cardiac Arrest, Using an Intent-to-Treat Analytical Approach
Group | Comparison | HR (95% CI) |
---|---|---|
Ventricular tachycardia | ||
HFrEF | HFrEF vs no HF | 7.01 (6.11-8.04) |
HFpEF | HFpEF vs no HF | 1.98 (1.69-2.34) |
Taking D or S | Taking D or S vs not taking D or S | 2.51 (1.96-3.21) |
HFrEF taking D or S | HFrEF taking D or S vs HFrEF not taking D or S | 1.35 (0.96-1.90) |
HFpEF taking D or S | HFpEF taking D or S vs HFpEF not taking D or S | 2.11 (1.08-4.12) |
Sudden cardiac arrest | ||
HFrEF | HFrEF vs no HF | 5.13 (4.05-6.50) |
HFpEF | HFpEF vs no HF | 2.54 (1.99-3.25) |
Taking D or S | Taking D or S vs not taking D or S | 1.24 (0.64-2.40) |
HFrEF taking D or S | HFrEF taking D or S vs HFrEF not taking D or S | 2.06 (0.76-5.61) |
HFpEF taking D or S | HFpEF taking D or S vs HFpEF not taking D or S | 0.72 (0.28-1.82) |
The multinomial propensity score method was used to select potential covariates (listed in Supplemental Tables 7 and 8), and any characteristics with SMDs larger than 0.1 (listed in Supplemental Tables 7 and 8) were incorporated into the final model for double adjustment. The inverse probability of treatment weighting was used to stabilize the covariates-induced differences and survival analysis for the recurrent events model was performed. HFrEF, HFpEF, and taking D or S are the main effects, and HFrEF taking D or S and HFpEF taking D or S are the interaction terms in the model.